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16 articles
  • COMMENTARIES

    β-blockers in septic shock: are we there yet?

    Revista Brasileira de Terapia Intensiva. 2017;29(1):1-3

    Abstract

    COMMENTARIES

    β-blockers in septic shock: are we there yet?

    Revista Brasileira de Terapia Intensiva. 2017;29(1):1-3

    DOI 10.5935/0103-507X.20170001

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    Background Septic shock is characterized by circulatory collapse and diminished tissue perfusion, leading to organ dysfunction in the setting of systemic infection. The mechanisms of septic shock are incompletely understood; moreover, its incidence is increasing, and its mortality remains unacceptably high. In addition to antimicrobial and supportive treatments, no other therapy has a survival benefit, […]
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  • RELATOS DE CASO

    Use of noninvasive ventilation in severe acute respiratory distress syndrome due to accidental chlorine inhalation: a case report

    Revista Brasileira de Terapia Intensiva. 2017;29(1):105-110

    Abstract

    RELATOS DE CASO

    Use of noninvasive ventilation in severe acute respiratory distress syndrome due to accidental chlorine inhalation: a case report

    Revista Brasileira de Terapia Intensiva. 2017;29(1):105-110

    DOI 10.5935/0103-507X.20170015

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    ABSTRACT

    Acute respiratory distress syndrome is characterized by diffuse inflammatory lung injury and is classified as mild, moderate, and severe. Clinically, hypoxemia, bilateral opacities in lung images, and decreased pulmonary compliance are observed. Sepsis is one of the most prevalent causes of this condition (30 - 50%). Among the direct causes of acute respiratory distress syndrome, chlorine inhalation is an uncommon cause, generating mucosal and airway irritation in most cases. We present a case of severe acute respiratory distress syndrome after accidental inhalation of chlorine in a swimming pool, with noninvasive ventilation used as a treatment with good response in this case. We classified severe acute respiratory distress syndrome based on an oxygen partial pressure/oxygen inspired fraction ratio <100, although the Berlin classification is limited in considering patients with severe hypoxemia managed exclusively with noninvasive ventilation. The failure rate of noninvasive ventilation in cases of acute respiratory distress syndrome is approximately 52% and is associated with higher mortality. The possible complications of using noninvasive positive-pressure mechanical ventilation in cases of acute respiratory distress syndrome include delays in orotracheal intubation, which is performed in cases of poor clinical condition and with high support pressure levels, and deep inspiratory efforts, generating high tidal volumes and excessive transpulmonary pressures, which contribute to ventilation-related lung injury. Despite these complications, some studies have shown a decrease in the rates of orotracheal intubation in patients with acute respiratory distress syndrome with low severity scores, hemodynamic stability, and the absence of other organ dysfunctions.

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    Use of noninvasive ventilation in severe acute respiratory distress syndrome due to accidental chlorine inhalation: a case report
  • BRIEF COMMUNICATION

    High prevalence of burnout syndrome among intensivists of the city of Porto Alegre

    Revista Brasileira de Terapia Intensiva. 2017;29(1):115-120

    Abstract

    BRIEF COMMUNICATION

    High prevalence of burnout syndrome among intensivists of the city of Porto Alegre

    Revista Brasileira de Terapia Intensiva. 2017;29(1):115-120

    DOI 10.5935/0103-507X.20170017

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    INTRODUCTION Burnout syndrome involves emotional exhaustion (EE), depersonalization (DP) and reduced personal achievement (PA).(,) Burnout is associated with absenteeism, physical illnesses, emotional problems, poor work performance and negative attitudes() and may result in decreased quality of medical care. The most widely used burnout syndrome measurement tool is the Maslach Burnout Inventory (MBI).() Variations in burnout […]
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    High prevalence of burnout syndrome among intensivists of the city of Porto Alegre
  • ARTIGOS ORIGINAIS

    Acute bag-valve breathing maneuvers plus manual chest compression is safe during stable septic shock: a randomized clinical trial

    Revista Brasileira de Terapia Intensiva. 2017;29(1):14-22

    Abstract

    ARTIGOS ORIGINAIS

    Acute bag-valve breathing maneuvers plus manual chest compression is safe during stable septic shock: a randomized clinical trial

    Revista Brasileira de Terapia Intensiva. 2017;29(1):14-22

    DOI 10.5935/0103-507X.20170004

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    ABSTRACT

    Objective:

    To evaluate the effects of bag-valve breathing maneuvers combined with standard manual chest compression techniques on safety, hemodynamics and oxygenation in stable septic shock patients.

    Design:

    A parallel, assessor-blinded, randomized trial of two groups. A computer-generated list of random numbers was prepared by an independent researcher to allocate treatments.

    Setting:

    The Intensive Care Unit at Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul.

    Participants:

    Fifty-two subjects were assessed for eligibility, and 32 were included. All included subjects (n = 32) received the allocated intervention (n = 19 for the Experimental Group and n = 13 for the Control Group).

    Intervention:

    Twenty minutes of bag-valve breathing maneuvers combined with manual chest compression techniques (Experimental Group) or chest compression, as routinely used at our intensive care unit (Control Group). Follow-up was performed immediately after and at 30 minutes after the intervention.

    Main outcome measure:

    Mean artery pressure.

    Results:

    All included subjects completed the trial (N = 32). We found no relevant effects on mean artery pressure (p = 0.17), heart rate (p = 0.50) or mean pulmonary artery pressure (p = 0.89) after adjusting for subject age and weight. Both groups were identical regarding oxygen consumption after the data adjustment (p = 0.84). Peripheral oxygen saturation tended to increase over time in both groups (p = 0.05), and there was no significant association between cardiac output and venous oxygen saturation (p = 0.813). No clinical deterioration was observed.

    Conclusion:

    A single session of bag-valve breathing maneuvers combined with manual chest compression is hemodynamically safe for stable septic-shocked subjects over the short-term.

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    Acute bag-valve breathing maneuvers plus manual chest compression is safe during stable septic shock: a randomized clinical trial
  • ARTIGOS ORIGINAIS

    Predictors and pattern of weaning and long-term outcome of patients with prolonged mechanical ventilation at an acute intensive care unit in North India

    Revista Brasileira de Terapia Intensiva. 2017;29(1):23-33

    Abstract

    ARTIGOS ORIGINAIS

    Predictors and pattern of weaning and long-term outcome of patients with prolonged mechanical ventilation at an acute intensive care unit in North India

    Revista Brasileira de Terapia Intensiva. 2017;29(1):23-33

    DOI 10.5935/0103-507X.20170005

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    ABSTRACT

    Objective:

    This study aimed to examine the clinical characteristics, weaning pattern, and outcome of patients requiring prolonged mechanical ventilation in acute intensive care unit settings in a resource-limited country.

    Methods:

    This was a prospective single-center observational study in India, where all adult patients requiring prolonged ventilation were followed for weaning duration and pattern and for survival at both intensive care unit discharge and at 12 months. The definition of prolonged mechanical ventilation used was that of the National Association for Medical Direction of Respiratory Care.

    Results:

    During the one-year period, 49 patients with a mean age of 49.7 years had prolonged ventilation; 63% were male, and 84% had a medical illness. The median APACHE II and SOFA scores on admission were 17 and 9, respectively. The median number of ventilation days was 37. The most common reason for starting ventilation was respiratory failure secondary to sepsis (67%). Weaning was initiated in 39 (79.5%) patients, with success in 34 (87%). The median weaning duration was 14 (9.5 - 19) days, and the median length of intensive care unit stay was 39 (32 - 58.5) days. Duration of vasopressor support and need for hemodialysis were significant independent predictors of unsuccessful ventilator liberation. At the 12-month follow-up, 65% had survived.

    Conclusion:

    In acute intensive care units, more than one-fourth of patients with invasive ventilation required prolonged ventilation. Successful weaning was achieved in two-thirds of patients, and most survived at the 12-month follow-up.

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    Predictors and pattern of weaning and long-term outcome of patients with prolonged mechanical ventilation at an acute intensive care unit in North India
  • ARTIGOS ORIGINAIS

    Brazilian version of the Functional Status Score for the ICU: translation and cross-cultural adaptation

    Revista Brasileira de Terapia Intensiva. 2017;29(1):34-38

    Abstract

    ARTIGOS ORIGINAIS

    Brazilian version of the Functional Status Score for the ICU: translation and cross-cultural adaptation

    Revista Brasileira de Terapia Intensiva. 2017;29(1):34-38

    DOI 10.5935/0103-507X.20170006

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    ABSTRACT

    Objective:

    The aim of the present study was to translate and cross-culturally adapt the Functional Status Score for the intensive care unit (FSS-ICU) into Brazilian Portuguese.

    Methods:

    This study consisted of the following steps: translation (performed by two independent translators), synthesis of the initial translation, back-translation (by two independent translators who were unaware of the original FSS-ICU), and testing to evaluate the target audience's understanding. An Expert Committee supervised all steps and was responsible for the modifications made throughout the process and the final translated version.

    Results:

    The testing phase included two experienced physiotherapists who assessed a total of 30 critical care patients (mean FSS-ICU score = 25 ± 6). As the physiotherapists did not report any uncertainties or problems with interpretation affecting their performance, no additional adjustments were made to the Brazilian Portuguese version after the testing phase. Good interobserver reliability between the two assessors was obtained for each of the 5 FSS-ICU tasks and for the total FSS-ICU score (intraclass correlation coefficients ranged from 0.88 to 0.91).

    Conclusion:

    The adapted version of the FSS-ICU in Brazilian Portuguese was easy to understand and apply in an intensive care unit environment.

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  • ARTIGOS ORIGINAIS

    Reducing pressure ulcers in patients with prolonged acute mechanical ventilation: a quasi-experimental study

    Revista Brasileira de Terapia Intensiva. 2017;29(1):39-46

    Abstract

    ARTIGOS ORIGINAIS

    Reducing pressure ulcers in patients with prolonged acute mechanical ventilation: a quasi-experimental study

    Revista Brasileira de Terapia Intensiva. 2017;29(1):39-46

    DOI 10.5935/0103-507X.20170007

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    ABSTRACT

    Objective:

    To determine the effectiveness of a quality management program in reducing the incidence and severity of pressure ulcers in critical care patients.

    Methods:

    This was a quasi-experimental, before-and-after study that was conducted in a medical-surgical intensive care unit. Consecutive patients who had received mechanical ventilation for ≥ 96 hours were included. A "Process Improvement" team designed a multifaceted interventional process that consisted of an educational session, a pressure ulcer checklist, a smartphone application for lesion monitoring and decision-making, and a "family prevention bundle".

    Results:

    Fifty-five patients were included in Pre-I group, and 69 were included in the Post-I group, and the incidence of pressure ulcers in these groups was 41 (75%) and 37 (54%), respectively. The median time for pressure ulcers to develop was 4.5 [4 - 5] days in the Pre-I group and 9 [6 - 20] days in the Post-I group after admission for each period. The incidence of advanced-grade pressure ulcers was 27 (49%) in the Pre-I group and 7 (10%) in the Post-I group, and finally, the presence of pressure ulcers at discharge was 38 (69%) and 18 (26%), respectively (p < 0.05 for all comparisons). Family participation totaled 9% in the Pre-I group and increased to 57% in the Post-I group (p < 0.05). A logistic regression model was used to analyze the predictors of advanced-grade pressure ulcers. The duration of mechanical ventilation and the presence of organ failure were positively associated with the development of pressure ulcers, while the multifaceted intervention program acted as a protective factor.

    Conclusion:

    A quality program based on both a smartphone application and family participation can reduce the incidence and severity of pressure ulcers in patients on prolonged acute mechanical ventilation.

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    Reducing pressure ulcers in patients with prolonged acute mechanical ventilation: a quasi-experimental study
  • COMMENTARIES

    Dear Sepsis-3, we are sorry to say that we don’t like you

    Revista Brasileira de Terapia Intensiva. 2017;29(1):4-8

    Abstract

    COMMENTARIES

    Dear Sepsis-3, we are sorry to say that we don’t like you

    Revista Brasileira de Terapia Intensiva. 2017;29(1):4-8

    DOI 10.5935/0103-507X.20170002

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    The controversy The medical community became divided over the clinical value of the new criteria (i.e., regarding their actual impact and safety when applied at the bedside). The criticism mainly focused on the following three aspects: (1) underlying theoretical concepts; (2) the methods used to define the criteria; and (3) their potential impacts on clinical […]
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    Dear Sepsis-3, we are sorry to say that we don’t like you

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