β-blockers in septic shock: are we there yet? - Critical Care Science (CCS)

Background

Septic shock is characterized by circulatory collapse and diminished tissue perfusion, leading to organ dysfunction in the setting of systemic infection. The mechanisms of septic shock are incompletely understood; moreover, its incidence is increasing, and its mortality remains unacceptably high. In addition to antimicrobial and supportive treatments, no other therapy has a survival benefit, despite multiple attempts at developing one.⁽⁾ With the article by Morelli et al.,⁽⁾ a new hope has emerged.

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