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18 articles
  • Jugular vein distensibility, a noninvasive parameter of fluid responsiveness?

    Rev Bras Ter Intensiva. 2015;27(3):190-192

    Abstract

    Jugular vein distensibility, a noninvasive parameter of fluid responsiveness?

    Rev Bras Ter Intensiva. 2015;27(3):190-192

    DOI 10.5935/0103-507X.20150039

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    Most critically ill patients in intensive care units (ICU) require fluid administration for volume expansion at some point during their hospital stay.() In most cases, initial volume expansion does not require more sophisticated or invasive measures. Clinical history data and clinical signs of low flow may suggest the likelihood of a response to the initial […]
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  • Patients with hematological malignancies admitted to intensive care units: new challenges for the intensivist

    Rev Bras Ter Intensiva. 2015;27(3):193-195

    Abstract

    Patients with hematological malignancies admitted to intensive care units: new challenges for the intensivist

    Rev Bras Ter Intensiva. 2015;27(3):193-195

    DOI 10.5935/0103-507X.20150040

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    Advances in treatment of cancer patients and improved understanding of pathophysiological mechanisms behind malignant diseases contribute to increased survival and, consequently, increasing needs of intensive care support for this population.() It should be highlighted that ‘cancer’ is a name generically given to a widely heterogeneous group of diseases; in comparison to solid tumors, hematological neoplasms […]
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  • PIRO and sepsis stratification: reality or a mirage?

    Rev Bras Ter Intensiva. 2015;27(3):196-198

    Abstract

    PIRO and sepsis stratification: reality or a mirage?

    Rev Bras Ter Intensiva. 2015;27(3):196-198

    DOI 10.5935/0103-507X.20150038

    Views2
    What is stratification? The objectives of staging systems are to stratify patients with a given disease according to their risk for adverse events, to assess their potential response to a given treatment, and to monitor their actual response. Such systems are widely used, and the Classification of Malignant Tumors (TNM) is the best-known of these […]
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  • Articles

    A guided approach to diagnose severe muscle weakness in the intensive care unit

    Rev Bras Ter Intensiva. 2015;27(3):199-201

    Abstract

    Articles

    A guided approach to diagnose severe muscle weakness in the intensive care unit

    Rev Bras Ter Intensiva. 2015;27(3):199-201

    DOI 10.5935/0103-507X.20150036

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    Intensive care unit (ICU) acquired muscle weakness (ICUAW) is a clinically detected condition characterized by diffuse, symmetric weakness involving the limbs and respiratory muscles.()Patients have different degrees of limb muscle weakness and are dependent on a ventilator, while the facial muscles are spared. Diagnosis of ICUAW requires that no plausible etiology other than critical illness […]
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    A guided approach to diagnose severe muscle weakness in the intensive care unit
  • Commentaries

    Corticosteroids for severe CAP: the pros

    Rev Bras Ter Intensiva. 2015;27(3):202-204

    Abstract

    Commentaries

    Corticosteroids for severe CAP: the pros

    Rev Bras Ter Intensiva. 2015;27(3):202-204

    DOI 10.5935/0103-507X.20150041

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    Severe community-acquired pneumonia (CAP) occurs in approximately 10% of hospitalized patients with CAP, and it still carries a high morbidity and mortality. In a multicenter study on severe pneumococcal CAP, the mortality of this population was 29%, with high rates of patients requiring mechanical ventilation and a shock.() Patients with severe CAP might die despite […]
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  • Original Articles

    Right internal jugular vein distensibility appears to be a surrogate marker for inferior vena cava vein distensibility for evaluating fluid responsiveness

    Rev Bras Ter Intensiva. 2015;27(3):205-211

    Abstract

    Original Articles

    Right internal jugular vein distensibility appears to be a surrogate marker for inferior vena cava vein distensibility for evaluating fluid responsiveness

    Rev Bras Ter Intensiva. 2015;27(3):205-211

    DOI 10.5935/0103-507X.20150042

    Views1

    ABSTRACT

    Objective:

    To investigate whether the respiratory variation of the inferior vena cava diameter (∆DIVC) and right internal jugular vein diameter (∆DRIJ) are correlated in mechanically ventilated patients.

    Methods:

    This study was a prospective clinical analysis in an intensive care unit at a university hospital. Thirty-nine mechanically ventilated patients with hemodynamic instability were included. ∆DIVC and ∆DRIJ were assessed by echography. Vein distensibility was calculated as the ratio of (A) Dmax - Dmin/Dmin and (B) Dmax - Dmin/ mean of Dmax - Dmin and expressed as a percentage.

    Results:

    ∆DIVC and ∆DRIJ were correlated by both methods: (A) r = 0.34, p = 0.04 and (B) r = 0.51, p = 0.001. Using 18% for ∆DIVC, indicating fluid responsiveness by method (A), 16 patients were responders and 35 measurements showed agreement (weighted Kappa = 0.80). The area under the ROC curve was 0.951 (95%CI 0.830 - 0.993; cutoff = 18.92). Using 12% for ∆DIVC, indicating fluid responsiveness by method (B), 14 patients were responders and 32 measurements showed agreement (weighted Kappa = 0.65). The area under the ROC curve was 0.903 (95%CI 0.765 - 0.973; cut-off value = 11.86).

    Conclusion:

    The respiratory variation of the inferior vena cava and the right internal jugular veins are correlated and showed significant agreement. Evaluation of right internal jugular vein distensibility appears to be a surrogate marker for inferior vena cava vein distensibility for evaluating fluid responsiveness.

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    Right internal jugular vein distensibility appears to be a surrogate marker for inferior vena cava vein distensibility for evaluating fluid responsiveness
  • Articles

    Main characteristics observed in patients with hematologic diseases admitted to an intensive care unit of a Brazilian university hospital

    Rev Bras Ter Intensiva. 2015;27(3):212-219

    Abstract

    Articles

    Main characteristics observed in patients with hematologic diseases admitted to an intensive care unit of a Brazilian university hospital

    Rev Bras Ter Intensiva. 2015;27(3):212-219

    DOI 10.5935/0103-507X.20150034

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    ABSTRACT

    Objective:

    To evaluate the clinical characteristics of patients with hematological disease admitted to the intensive care unit and the use of noninvasive mechanical ventilation in a subgroup with respiratory dysfunction.

    Methods:

    A retrospective observational study from September 2011 to January 2014.

    Results:

    Overall, 157 patients were included. The mean age was 45.13 (± 17.2) years and 46.5% of the patients were female. Sixty-seven (48.4%) patients had sepsis, and 90 (57.3%) patients required vasoactive vasopressors. The main cause for admission to the intensive care unit was acute respiratory failure (94.3%). Among the 157 studied patients, 47 (29.9%) were intubated within the first 24 hours, and 38 (24.2%) underwent noninvasive mechanical ventilation. Among the 38 patients who initially received noninvasive mechanical ventilation, 26 (68.4%) were subsequently intubated, and 12 (31.6%) responded to this mode of ventilation. Patients who failed to respond to noninvasive mechanical ventilation had higher intensive care unit mortality (66.7% versus 16.7%; p = 0.004) and a longer stay in the intensive care unit (9.6 days versus 4.6 days, p = 0.02) compared with the successful cases. Baseline severity scores (SOFA and SAPS 3) and the total leukocyte count were not significantly different between these two subgroups. In a multivariate logistic regression model including the 157 patients, intubation at any time during the stay in the intensive care unit and SAPS 3 were independently associated with intensive care unit mortality, while using noninvasive mechanical ventilation was not.

    Conclusion:

    In this retrospective study with severely ill hematologic patients, those who underwent noninvasive mechanical ventilation at admission and failed to respond to it presented elevated intensive care unit mortality. However, only intubation during the intensive care unit stay was independently associated with a poor outcome. Further studies are needed to define predictors of noninvasive mechanical ventilation failure.

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  • Maternal near miss in the intensive care unit: clinical and epidemiological aspects

    Rev Bras Ter Intensiva. 2015;27(3):220-227

    Abstract

    Maternal near miss in the intensive care unit: clinical and epidemiological aspects

    Rev Bras Ter Intensiva. 2015;27(3):220-227

    DOI 10.5935/0103-507X.20150033

    Views1

    ABSTRACT

    Objective:

    To analyze the epidemiological clinical profile of women with maternal near miss according to the new World Health Organization criteria.

    Methods:

    A descriptive crosssectional study was conducted, in which the records of patients admitted to the obstetric intensive care unit of a tertiary hospital in Recife (Brazil) over a period of four years were analyzed. Women who presented at least one near miss criterion were included. The variables studied were age, race/color, civil status, education, place of origin, number of pregnancies and prenatal consultations, complications and procedures performed, mode of delivery, gestational age at delivery, and maternal near miss criteria. The descriptive analysis was performed using the program Epi-Info 3.5.1.

    Results:

    Two hundred fifty-five cases of maternal near miss were identified, with an overall ratio of maternal near miss of 12.8/1,000 live births. Among these cases, 43.2% of the women had incomplete primary education, 44.7% were primiparous, and 20.5% had undergone a previous cesarean section. Regarding specific diagnoses, there was a predominance of hypertensive disorders (62.7%), many of which were complicated by HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome (41.2%). The laboratory near miss criteria were the most often observed (59.6%), due mainly to the high frequency of acute thrombocytopenia (32.5%).

    Conclusions:

    A high frequency of women who had a low level of education and who were primiparous was observed. According to the new criteria proposed by the World Health Organization, hypertensive pregnancy disorders are still the most common among maternal near miss cases. The high frequency of HELLP syndrome was also striking, which contributed to acute thrombocytopenia being the most frequent near miss criterion.

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    Maternal near miss in the intensive care unit: clinical and epidemiological aspects

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