You searched for:"Rogério Fernandes"
We found (4) results for your search.-
Original Articles
SOFA in the first 24 hours as an outcome predictor of acute liver failure
Rev Bras Ter Intensiva. 2018;30(1):64-70
Abstract
Original ArticlesSOFA in the first 24 hours as an outcome predictor of acute liver failure
Rev Bras Ter Intensiva. 2018;30(1):64-70
DOI 10.5935/0103-507X.20180012
Views2See moreABSTRACT
Objective:
To describe a cohort of patients with acute liver failure and to analyze the demographic and clinical factors associated with mortality.
Methods:
Retrospective cohort study in which all patients admitted for acute liver failure from July 28, 2012, to August 31, 2017, were included. Clinical and demographic data were collected using the Epimed System. The SAPS 3, SOFA, and MELD scores were measured. The odds ratios and 95% confidence intervals were estimated. Receiver operating characteristics curves were obtained for the prognostic scores, along with the Kaplan-Meier survival curve for the score best predicting mortality.
Results:
The majority of the 40 patients were female (77.5%), and the most frequent etiology was hepatitis B (n = 13). Only 35% of the patients underwent liver transplantation. The in-hospital mortality rate was 57.5% (95%CI: 41.5 – 73.5). Among the scores investigated, only SOFA remained associated with risk of death (OR = 1.37; 95%CI 1.11 – 1.69; p < 0.001). After SOFA stratification into < 12 and ≥ 12 points, survival was higher in patients with SOFA <12 (log-rank p < 0.001).
Conclusion:
SOFA score in the first 24 hours was the best predictor of fatal outcome.
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Case Reports
Immune reconstitution inflammatory syndrome as a cause of autoimmune hepatitis and acute liver failure
Rev Bras Ter Intensiva. 2017;29(3):382-385
Abstract
Case ReportsImmune reconstitution inflammatory syndrome as a cause of autoimmune hepatitis and acute liver failure
Rev Bras Ter Intensiva. 2017;29(3):382-385
DOI 10.5935/0103-507X.20170053
Views0ABSTRACT
Acute liver failure is a rare syndrome with high mortality and is often diagnosed late. Intensivist physicians play fundamental roles in the diagnostic suspicion and the management of the multiple-organic dysfunctions characteristic of this entity. Immune reconstitution inflammatory syndrome is an entity that is characterized by the paradoxical worsening of the patient’s previous condition, after the initiation of antiretrovirals, triggered against either pathogens present in the host or autoantigens. Autoimmune hepatitis has recently been described as one of these autoimmune manifestations. The authors report the first case with evolution to acute liver failure and death within a few days after the development of encephalopathy, review the cases of autoimmune hepatitis described and comment on the therapeutic possibilities in this context.
Keywords:Case reportsHepatitis, autoimmuneImmune reconstitution inflammatory syndromeLiver failure, acuteSee more -
Special Articles
Guidelines for the assessment and acceptance of potential brain-dead organ donors
Rev Bras Ter Intensiva. 2016;28(3):220-255
Abstract
Special ArticlesGuidelines for the assessment and acceptance of potential brain-dead organ donors
Rev Bras Ter Intensiva. 2016;28(3):220-255
DOI 10.5935/0103-507X.20160049
Views0See moreABSTRACT
Organ transplantation is the only alternative for many patients with terminal diseases. The increasing disproportion between the high demand for organ transplants and the low rate of transplants actually performed is worrisome. Some of the causes of this disproportion are errors in the identification of potential organ donors and in the determination of contraindications by the attending staff. Therefore, the aim of the present document is to provide guidelines for intensive care multi-professional staffs for the recognition, assessment and acceptance of potential organ donors.
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Special Articles
Guidelines for potential multiple organ donors (adult). Part III: organ-specific recommendations
Rev Bras Ter Intensiva. 2011;23(4):410-425
Abstract
Special ArticlesGuidelines for potential multiple organ donors (adult). Part III: organ-specific recommendations
Rev Bras Ter Intensiva. 2011;23(4):410-425
DOI 10.1590/S0103-507X2011000400005
Views0See moreBrain death (BD) alters the pathophysiology of patients and may damage the kidneys, the lungs, the heart and the liver. To obtain better quality transplant organs, intensive care physicians in charge of the maintenance of deceased donors should attentively monitor these organs. Careful hemodynamic, ventilatory and bronchial clearance management minimizes the loss of kidneys and lungs. The evaluation of cardiac function and morphology supports the transplant viability assessment of the heart. The monitoring of liver function, the management of the patient’s metabolic status and the evaluation of viral serology are fundamental for organ selection by the transplant teams and for the care of the transplant recipient
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Case reports Child Coronavirus infections COVID-19 Critical care Critical illness Extracorporeal membrane oxygenation Infant, newborn Intensive care Intensive care units Intensive care units, pediatric mechanical ventilation Mortality Physical therapy modalities Prognosis Respiration, artificial Respiratory insufficiency risk factors SARS-CoV-2 Sepsis