You searched for:"Antonio Paulo Nassar Jr"
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Editorial
Open-access publications: a double-edged sword for critical care researchers in lowand middle-income countries
Crit Care Sci. 2023;35(4):342-344
Abstract
EditorialOpen-access publications: a double-edged sword for critical care researchers in lowand middle-income countries
Crit Care Sci. 2023;35(4):342-344
DOI 10.5935/2965-2774.20230263-pt
Views39Open access model and lowand middle-income countries Open access journals usually exempt researchers from low-income countries from publication fees, and this exemption seems to favor the publication of articles by researchers from sub-Saharan Africa.() However, producing high-quality scientific research in these settings is challenging and often funded by agencies such as the National Institutes of […]See more -
Original Article
IMPACTO-MR: a Brazilian nationwide platform study to assess infections and multidrug resistance in intensive care units
Rev Bras Ter Intensiva. 2022;34(4):418-425
Abstract
Original ArticleIMPACTO-MR: a Brazilian nationwide platform study to assess infections and multidrug resistance in intensive care units
Rev Bras Ter Intensiva. 2022;34(4):418-425
DOI 10.5935/0103-507X.20220209-en
Views2ABSTRACT
Objective:
To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria.
Methods:
We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform.
Results:
The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database.
Conclusion:
The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials.
Keywords:bacterialBacterial infectionsDatabaseDatabase management systemsDrug-resistanceIMPACTO-MRIntensive care unitsSoftwareSee more -
Commentaries
Is APACHE II a useful tool for clinical research?
Rev Bras Ter Intensiva. 2017;29(3):264-267
Abstract
CommentariesIs APACHE II a useful tool for clinical research?
Rev Bras Ter Intensiva. 2017;29(3):264-267
DOI 10.5935/0103-507X.20170046
Views0The population of patients admitted to the intensive care unit (ICU) is quite heterogeneous. Overall, the outcome of ICU treatment depends on the site, cause of admission, age, prior comorbidities, and acute physiological changes at admission and during the first several hours of treatment. Predictions of the in-hospital mortality of ICU patients play important roles […]See more -
Review Articles
Applicability of respiratory variations in stroke volume and its surrogates for dynamic fluid responsiveness prediction in critically ill patients: a systematic review of the prevalence of required conditions
Rev Bras Ter Intensiva. 2017;29(1):70-76
Abstract
Review ArticlesApplicability of respiratory variations in stroke volume and its surrogates for dynamic fluid responsiveness prediction in critically ill patients: a systematic review of the prevalence of required conditions
Rev Bras Ter Intensiva. 2017;29(1):70-76
DOI 10.5935/0103-507X.20170011
Views0See moreABSTRACT
Objective:
The present systematic review searched for published data on the prevalence of required conditions for proper assessment in critically ill patients.
Methods:
The Medline, Scopus and Web of Science databases were searched to identify studies that evaluated the prevalence of validated conditions for the fluid responsiveness assessment using respiratory variations in the stroke volume or another surrogate in adult critically ill patients. The primary outcome was the suitability of the fluid responsiveness evaluation. The secondary objectives were the type and prevalence of pre-requisites evaluated to define the suitability.
Results:
Five studies were included (14,804 patients). High clinical and statistical heterogeneity was observed (I2 = 98.6%), which prevented us from pooling the results into a meaningful summary conclusion. The most frequent limitation identified is the absence of invasive mechanical ventilation with a tidal volume ≥ 8mL/kg. The final suitability for the fluid responsiveness assessment was low (in four studies, it varied between 1.9 to 8.3%, in one study, it was 42.4%).
Conclusion:
Applicability of the dynamic indices of preload responsiveness requiring heart-lung interactions might be limited in daily practice.
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KEY WORDS
Case reports Child Coronavirus infections COVID-19 Critical care Critical illness ICU Infant, newborn Intensive care Intensive care units Intensive care units, pediatric mechanical ventilation Mortality Physical therapy modalities Prognosis Respiration, artificial Respiratory insufficiency risk factors SARS-CoV-2 Sepsis