You searched for:"Marina Bessel"
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Original Article
Clinical characteristics and predictors of mechanical ventilation in patients with COVID-19 hospitalized in Southern Brazil
- Gisele Alsina Nader Bastos,
- Aline Zimmermann de Azambuja,
- Carisi Anne Polanczyk,
- Débora Dalmas Gräf,
- Isabelle Weschenfelder Zorzo, [ … ],
- Marcelo Comerlato Scotta
Abstract
Original ArticleClinical characteristics and predictors of mechanical ventilation in patients with COVID-19 hospitalized in Southern Brazil
Rev Bras Ter Intensiva. 2020;32(4):487-492
DOI 10.5935/0103-507X.20200082
- Gisele Alsina Nader Bastos,
- Aline Zimmermann de Azambuja,
- Carisi Anne Polanczyk,
- Débora Dalmas Gräf,
- Isabelle Weschenfelder Zorzo,
- Juçara Gasparetto Maccari,
- Lúcia Schnor Haygert,
- Luiz Antônio Nasi,
- Marcelo Basso Gazzana,
- Marina Bessel,
- Paulo Márcio Pitrez,
- Roselaine Pinheiro de Oliveira,
- Marcelo Comerlato Scotta
Views1Abstract
Objective:
This study aims to describe the clinical characteristics and predictors of mechanical ventilation of adult inpatients with COVID-19 in a single center.
Methods:
A retrospective cohort study was performed and included adult inpatients hospitalized from March 17th to May 3rd, 2020, who were diagnosed with SARS-CoV-2 infection. Clinical and demographic characteristics were extracted from electronic medical records.
Results:
Overall, 88 consecutive patients were included in this study. The median age of the patients was 63 years (IQR 49 – 71); 59 (67%) were male, 65 (86%) had a college degree and 67 (76%) had at least one comorbidity. Twenty-nine (33%) patients were admitted to the intensive care unit, 18 (20%) patients needed mechanical ventilation, and 9 (10.2%) died during hospitalization. The median length of stay in the intensive care unit and the median duration of mechanical ventilation was 23 and 29.5 days, respectively. An age ≥ 65 years was an independent risk factor for mechanical ventilation (OR 8.4 95%CI 1.3 – 55.6 p = 0.02).
Conclusion:
Our findings describe the first wave of Brazilian patients hospitalized for COVID-19. Age was the strongest predictor of respiratory insufficiency and the need for mechanical ventilation in our population.
Keywords:cohort studiesCoronavirus infectionsCOVID-19PandemicsRespiration, artificialrisk factorsSARS-CoV-2See moreViews1
Abstract
Original ArticleClinical characteristics and predictors of mechanical ventilation in patients with COVID-19 hospitalized in Southern Brazil
Rev Bras Ter Intensiva. 2020;32(4):487-492
DOI 10.5935/0103-507X.20200082
- Gisele Alsina Nader Bastos,
- Aline Zimmermann de Azambuja,
- Carisi Anne Polanczyk,
- Débora Dalmas Gräf,
- Isabelle Weschenfelder Zorzo,
- Juçara Gasparetto Maccari,
- Lúcia Schnor Haygert,
- Luiz Antônio Nasi,
- Marcelo Basso Gazzana,
- Marina Bessel,
- Paulo Márcio Pitrez,
- Roselaine Pinheiro de Oliveira,
- Marcelo Comerlato Scotta
Views1Abstract
Objective:
This study aims to describe the clinical characteristics and predictors of mechanical ventilation of adult inpatients with COVID-19 in a single center.
Methods:
A retrospective cohort study was performed and included adult inpatients hospitalized from March 17th to May 3rd, 2020, who were diagnosed with SARS-CoV-2 infection. Clinical and demographic characteristics were extracted from electronic medical records.
Results:
Overall, 88 consecutive patients were included in this study. The median age of the patients was 63 years (IQR 49 – 71); 59 (67%) were male, 65 (86%) had a college degree and 67 (76%) had at least one comorbidity. Twenty-nine (33%) patients were admitted to the intensive care unit, 18 (20%) patients needed mechanical ventilation, and 9 (10.2%) died during hospitalization. The median length of stay in the intensive care unit and the median duration of mechanical ventilation was 23 and 29.5 days, respectively. An age ≥ 65 years was an independent risk factor for mechanical ventilation (OR 8.4 95%CI 1.3 – 55.6 p = 0.02).
Conclusion:
Our findings describe the first wave of Brazilian patients hospitalized for COVID-19. Age was the strongest predictor of respiratory insufficiency and the need for mechanical ventilation in our population.
Keywords:cohort studiesCoronavirus infectionsCOVID-19PandemicsRespiration, artificialrisk factorsSARS-CoV-2See more -
Original Articles
Functional ability in younger and older elderlies after discharge from the intensive care unit. A prospective cohort
Rev Bras Ter Intensiva. 2017;29(3):293-302
Abstract
Original ArticlesFunctional ability in younger and older elderlies after discharge from the intensive care unit. A prospective cohort
Rev Bras Ter Intensiva. 2017;29(3):293-302
DOI 10.5935/0103-507X.20170055
Views0See moreABSTRACT
Objective:
To compare the functional capacity of younger elderly individuals (60 to 79 years old) with that of older elderly individuals (≥ 80 years old) during the first 6 months after discharge from the intensive care unit.
Methods:
A multicenter prospective cohort study was conducted, in which data on intensive care unit admission and outcomes after hospital discharge (immediate post-discharge, after 3 months and after 6 months) were collected. Muscle strength was evaluated through the protocol of the Medical Research Council and dynamometry (handgrip); the ability to perform activities of daily life and functional independence were assessed by the Barthel index and the usual level of physical activity (International Physical Activity Questionnaire); and quality of life was assessed by the 12-Item Short-Form Health Survey Version 2.
Results:
Among the 253 patients included, 167 were younger elderly (between 61 and 79 years old), and 86 were older elderly (≥ 80 years old). During the sixth month of evaluation, the older elderlies presented a higher need for a caregiver (69.0% versus 49, 5%, p = 0.002). Functional capacity prior to intensive care unit admission and in the third month after discharge was lower in older elderlies than in younger ones (Barthel prior to the intensive care unit: 73.0 ± 30.0 versus 86.5 ± 22.6; p <0.001, Barthel in the third month: 63.5 ± 34.0 versus 71.5 ± 35.5, p = 0.03), as was the usual level of physical activity (International Physical Activity Questionnaire in the third month: active/very active 3.4% versus 18.3%, no physical activity 64.4% versus 39.7%, p < 0.001, and International Physical Activity Questionnaire in the sixth month: active/very active 5.8% versus 20.8%, no physical activity 69.2% versus 43.4%, p = 0.005). Older elderlies had lower muscle strength when assessed according to handgrip in both the dominant (14.5 ± 7.7 versus 19.9 ± 9.6, p = 0.008) and non-dominant limb (13.1 ± 6.7 versus 17.5 ± 9.1, p = 0.02). There were no differences in functional capacity loss or reported quality of life between the age groups.
Conclusion:
Although there were great functional capacity losses after discharge from the intensive care unit in both age groups, there was no difference in the magnitude of functional capacity loss between younger (60 to 79 years) and older elderly individuals (≥ 80 years old) during the first 6 months after discharge from the intensive care unit.
Views0Abstract
Original ArticlesFunctional ability in younger and older elderlies after discharge from the intensive care unit. A prospective cohort
Rev Bras Ter Intensiva. 2017;29(3):293-302
DOI 10.5935/0103-507X.20170055
Views0See moreABSTRACT
Objective:
To compare the functional capacity of younger elderly individuals (60 to 79 years old) with that of older elderly individuals (≥ 80 years old) during the first 6 months after discharge from the intensive care unit.
Methods:
A multicenter prospective cohort study was conducted, in which data on intensive care unit admission and outcomes after hospital discharge (immediate post-discharge, after 3 months and after 6 months) were collected. Muscle strength was evaluated through the protocol of the Medical Research Council and dynamometry (handgrip); the ability to perform activities of daily life and functional independence were assessed by the Barthel index and the usual level of physical activity (International Physical Activity Questionnaire); and quality of life was assessed by the 12-Item Short-Form Health Survey Version 2.
Results:
Among the 253 patients included, 167 were younger elderly (between 61 and 79 years old), and 86 were older elderly (≥ 80 years old). During the sixth month of evaluation, the older elderlies presented a higher need for a caregiver (69.0% versus 49, 5%, p = 0.002). Functional capacity prior to intensive care unit admission and in the third month after discharge was lower in older elderlies than in younger ones (Barthel prior to the intensive care unit: 73.0 ± 30.0 versus 86.5 ± 22.6; p <0.001, Barthel in the third month: 63.5 ± 34.0 versus 71.5 ± 35.5, p = 0.03), as was the usual level of physical activity (International Physical Activity Questionnaire in the third month: active/very active 3.4% versus 18.3%, no physical activity 64.4% versus 39.7%, p < 0.001, and International Physical Activity Questionnaire in the sixth month: active/very active 5.8% versus 20.8%, no physical activity 69.2% versus 43.4%, p = 0.005). Older elderlies had lower muscle strength when assessed according to handgrip in both the dominant (14.5 ± 7.7 versus 19.9 ± 9.6, p = 0.008) and non-dominant limb (13.1 ± 6.7 versus 17.5 ± 9.1, p = 0.02). There were no differences in functional capacity loss or reported quality of life between the age groups.
Conclusion:
Although there were great functional capacity losses after discharge from the intensive care unit in both age groups, there was no difference in the magnitude of functional capacity loss between younger (60 to 79 years) and older elderly individuals (≥ 80 years old) during the first 6 months after discharge from the intensive care unit.
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KEY WORDS
Case reports Child Coronavirus infections COVID-19 Critical care Critical illness Extracorporeal membrane oxygenation Infant, newborn Intensive care Intensive care units Intensive care units, pediatric mechanical ventilation Mortality Physical therapy modalities Prognosis Respiration, artificial Respiratory insufficiency risk factors SARS-CoV-2 Sepsis