Tackling healthcare-associated infections in Brazilian intensive care units: we need more than collaboration - Critical Care Science (CCS)

Editorial

Tackling healthcare-associated infections in Brazilian intensive care units: we need more than collaboration

Healthcare-associated infections (HAIs) and antimicrobial resistance (AMRs) demand a global effort for their containment.() Healthcare-associated infections have an estimated prevalence between 7 and 10% worldwide, whereas the incidence is greater than 15% in developing countries. This difference is more remarkable when comparing the incidence of HAIs in intensive care units (ICUs) with estimated values of 47.9 per 1,000 patient days in developing countries and 13.9 per 1,000 patient days in the United States.()

The impact of HAIs is wide in scope. Patients diagnosed with HAIs have a longer length of stay (LOS) and higher mortality, especially when infections are associated with antimicrobial resistance.(,) Cassini et al. demonstrated that greater than 670,000 patients died from AMR in 2015, and 63.5% of cases were healthcare associated. These infections were also associated with a significant number of disability-adjusted life-years.() Approximately US$15 billion were spent in 2016 on HAIs, and approximately €8,500 to 34,000 more were spent per infection due to longer LOS and additional treatment, as estimated by the Organização para a Cooperação e Desenvolvimento Econômico (OECD).(,)

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