Reply to: Critical COVID-19 and neurological dysfunction - a direct comparative analysis between SARS-CoV-2 and other infectious pathogens - Critical Care Science (CCS)
Crit Care Sci. 2023;35(3):337-337
The authors thank Dr. Magoon and Dr. Suresh for the letter and for their interest in our study “Critical COVID-19 and neurological dysfunction – a direct comparative analysis between SARS-CoV-2 and other infectious pathogens”.()
We start by highlighting the importance and pertinence of the first comment in the letter. Indeed, in our analysis, COVID-19 patients spent significantly more days under sedoanalgesia, despite the absence of a significant association between this variable and the presence of neurological dysfunction. Therefore, it is unlikely that this variable could have biased our results. However, we have not performed an in-depth characterization of the nature of the sedation of these patients; nonetheless, we must point out that, in our center, there is a protocol for critical care patients sedation using the ABCDEF bundle as a standard of care.()
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The authors thank Dr. Magoon and Dr. Suresh for the letter and for their interest in our study “Critical COVID-19 and neurological dysfunction - a direct comparative analysis between SARS-CoV-2 and other infectious pathogens”.()
We start by highlighting the importance and pertinence of the first comment in the letter. Indeed, in our analysis, COVID-19 patients spent significantly more days under sedoanalgesia, despite the absence of a significant association between this variable and the presence of neurological dysfunction. Therefore, it is unlikely that this variable could have biased our results. However, we have not performed an in-depth characterization of the nature of the sedation of these patients; nonetheless, we must point out that, in our center, there is a protocol for critical care patients sedation using the ABCDEF bundle as a standard of care.()
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