CD4+CD25+ T lymphocytes and regulation of the immune system: perspectives for a pathophysiological understanding of sepsis - Critical Care Science (CCS)
The systemic inflammatory response represents the core pathogenic event of sepsis, underlying clinical manifestations and laboratory findings in patients. Numerous studies have shown that CD4+CD25+ T lymphocytes, also known as regulatory T lymphocytes (Treg), participate in the development of sepsis due to their ability to suppress the immune response. The present article discusses the role of Treg lymphocytes in sepsis based on a specific search strategy (Latin American and Caribbean Health Sciences / Literatura Latino-americana e do Caribe em Ciências da Saúde – LILACS, PubMed, and Scientific Electronic Library Online – SciELO) focusing on two main topics: the participation of Treg cells in inflammation and immunity as well as perspectives in the computational physiological investigation of sepsis.
Siqueira-Batista R, Gomes AP, Azevedo SFM, Vitorino RR, Mendonça EG, Sousa FO, Oliveira AP, et al. CD4+CD25+ T lymphocytes and regulation of the immune system: perspectives for a pathophysiological understanding of sepsis. Rev Bras Ter Intensiva 2012;24(3):294-301.
Electronic Document Format (ABNT)
Siqueira-Batista, Rodrigo; Gomes, Andréia Patrícia; Azevedo, Sarah Fumian Milward; Vitorino, Rodrigo Roger; Mendonça, Eduardo Gomes de; Sousa, Flávio Oliveira de; Oliveira, Alcione de Paiva; Cerqueira, Fábio Ribeiro; Paula, Sérgio Oliveira de; Oliveira, Maria Goreti de Almeida. CD4+CD25+ T lymphocytes and regulation of the immune system: perspectives for a pathophysiological understanding of sepsis. Rev Bras Ter Intensiva, v. 24, n. 3, p. 294-301, Nov. 2012.
Electronic Document Format (APA)
Siqueira-Batista, R., Gomes, A. P., Azevedo, S. F. M., Vitorino, R. R., Mendonça, E. G. , Sousa, F. O. , Oliveira, A. P., Cerqueira, F. R., Paula, S. O. , & Oliveira, M. G. A. (2012). CD4+CD25+ T lymphocytes and regulation of the immune system: perspectives for a pathophysiological understanding of sepsis. Rev Bras Ter Intensiva, 24(3), 294-301.
Electronic Document Format (ISO)
Siqueira-Batista, Rodrigo and Gomes, Andréia Patrícia and Azevedo, Sarah Fumian Milward and Vitorino, Rodrigo Roger and Mendonça, Eduardo Gomes de and Sousa, Flávio Oliveira de and Oliveira, Alcione de Paiva and Cerqueira, Fábio Ribeiro and Paula, Sérgio Oliveira de and Oliveira, Maria Goreti de Almeida. CD4+CD25+ T lymphocytes and regulation of the immune system: perspectives for a pathophysiological understanding of sepsis. Rev Bras Ter Intensiva [online]. 2012, vol. 24, n. 3, [cited 2024-05-20], pp.294-301. Available from: <https://criticalcarescience.org/article/cd4cd25-t-lymphocytes-and-regulation-of-the-immune-system-perspectives-for-a-pathophysiological-understanding-of-sepsis/>.
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