Sepsis is an important healthcare burden in Latin America: a call to action! - Critical Care Science (CCS)
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. The precise incidence of sepsis is unknown and there is a lack of populational studies on the disease, especially from low and middle-income countries. However, extrapolations of populational data from high-income countries suggest a number of 30 million sepsis cases annually worldwide with approximately 6 million deaths.() In Latin-American (LATAM) countries, the few available studies also suggest that sepsis represents a significant healthcare issue. A previous study from Brazil demonstrated that infection-associated organ dysfunction was related to up to 22% of all deaths in the country in 2010.() In Brazilian intensive care units (ICUs), sepsis prevalence is 30% and hospital mortality rate for ICU patients is 55%.() Studies from Colombia and Argentina also reported mortality rates for septic shock ranging from 45.6% to 51%.(,) Reasons for this significant burden of sepsis may include areas with inadequate provision of clean water, sanitation and nutrition, inadequate vaccination, as well as reduced awareness of sepsis among lay people and healthcare personnel, low access to intensive care services and an increased incidence of healthcare-associated infections.()
In order to tackle the burden of sepsis worldwide, in 2012 the Global Sepsis Alliance (GSA) created the first World Sepsis Day (WSD) as a launch platform for the World Sepsis Declaration. The purposes of WSD are to increase the perception of sepsis importance among lay public, healthcare workers and policy makers and to encourage quality improvement programs for sepsis early identification and treatment. Since then, initiatives to improve sepsis awareness have increased worldwide with events for lay public, healthcare staff and policy makers. These initiatives have culminated with the approval on May 26th, 2017 of a sepsis resolution (WHA70.7) by the World Health Organization (WHO).() The WHO resolution recognizes sepsis as a major threat to patient safety and global health and urges the member states to start initiatives to improve sepsis prevention, recognition and treatment. This resolution has the potential to save millions of lives, however for that happening it requires coordinated efforts by politicians, policymakers, health care administrators, researchers, and clinicians working in all health care settings.()
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Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. The precise incidence of sepsis is unknown and there is a lack of populational studies on the disease, especially from low and middle-income countries. However, extrapolations of populational data from high-income countries suggest a number of 30 million sepsis cases annually worldwide with approximately 6 million deaths.() In Latin-American (LATAM) countries, the few available studies also suggest that sepsis represents a significant healthcare issue. A previous study from Brazil demonstrated that infection-associated organ dysfunction was related to up to 22% of all deaths in the country in 2010.() In Brazilian intensive care units (ICUs), sepsis prevalence is 30% and hospital mortality rate for ICU patients is 55%.() Studies from Colombia and Argentina also reported mortality rates for septic shock ranging from 45.6% to 51%.(,) Reasons for this significant burden of sepsis may include areas with inadequate provision of clean water, sanitation and nutrition, inadequate vaccination, as well as reduced awareness of sepsis among lay people and healthcare personnel, low access to intensive care services and an increased incidence of healthcare-associated infections.()
In order to tackle the burden of sepsis worldwide, in 2012 the Global Sepsis Alliance (GSA) created the first World Sepsis Day (WSD) as a launch platform for the World Sepsis Declaration. The purposes of WSD are to increase the perception of sepsis importance among lay public, healthcare workers and policy makers and to encourage quality improvement programs for sepsis early identification and treatment. Since then, initiatives to improve sepsis awareness have increased worldwide with events for lay public, healthcare staff and policy makers. These initiatives have culminated with the approval on May 26th, 2017 of a sepsis resolution (WHA70.7) by the World Health Organization (WHO).() The WHO resolution recognizes sepsis as a major threat to patient safety and global health and urges the member states to start initiatives to improve sepsis prevention, recognition and treatment. This resolution has the potential to save millions of lives, however for that happening it requires coordinated efforts by politicians, policymakers, health care administrators, researchers, and clinicians working in all health care settings.()
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