Mandibular fracture due to rare manifestation of Langerhans cell histiocytosis - Critical Care Science (CCS)

Dear Editor,

Langerhans cell histiocytosis (LCH) is reported as being rare in the literature, with an incidence of 5 cases per 1 million per year and a prevalence of 3.7:1 in men:women. LCH is generally limited to an organ, most commonly lesions of the bone, whether solitary or multiple, that tend to appear in the cranial or femoral region in children younger than 10 years and in the costal arches, scapula or mandible in patients up to 20 years of age.^(–) The diagnosis is based on clinical symptoms, radiographic symptoms and especially histological examination after biopsy.

[…]