Você pesquisou por y - Critical Care Science (CCS)

You searched for:"Sandeep Grover"

We found (1) results for your search.
  • Original Article

    Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial

    Crit Care Sci. 2024;36:e20240144en

    Abstract

    Original Article

    Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial

    Crit Care Sci. 2024;36:e20240144en

    DOI 10.62675/2965-2774.20240144-pt

    Views1,131

    ABSTRACT

    Objective:

    To determine whether enteral melatonin decreases the incidence of delirium in critically ill adults.

    Methods:

    In this randomized controlled trial, adults were admitted to the intensive care unit and received either usual standard care alone (Control Group) or in combination with 3mg of enteral melatonin once a day at 9 PM (Melatonin Group). Concealment of allocation was done by serially numbered opaque sealed envelopes. The intensivist assessing delirium and the investigator performing the data analysis were blinded to the group allocation. The primary outcome was the incidence of delirium within 24 hours of the intensive care unit stay. The secondary outcomes were the incidence of delirium on Days 3 and 7, intensive care unit mortality, length of intensive care unit stay, duration of mechanical ventilation and Glasgow outcome score (at discharge).

    Results:

    We included 108 patients in the final analysis, with 54 patients in each group. At 24 hours of intensive care unit stay, there was no difference in the incidence of delirium between Melatonin and Control Groups (29.6 versus 46.2%; RR = 0.6; 95%CI 0.38 - 1.05; p = 0.11). No secondary outcome showed a statistically significant difference.

    Conclusion:

    Enteral melatonin 3mg is not more effective at decreasing the incidence of delirium than standard care is in critically ill adults.

    See more
    Efficacy of melatonin in decreasing the incidence of delirium in critically ill adults: a randomized controlled trial

Search

Search in:

Article type
article-commentary
brief-report
case-report
case-report
correction
editorial
editorial
letter
letter
other
rapid-communication
reply
research-article
research-article
review-article
review-article
Section
Articles
Artigo de Revisão de Pediatria
Artigo Original
Artigo Original de Pediatria
Artigo Original Destaque
Artigos de Revisão
Artigos de Revisão
Artigos originais
Author's Response
Brief Communication
Case Report
Case Reports
Clinical Report
Comentários
Commentaries
Commentary
Consenso Brasileiro de Monitorização e Suporte Hemodinâmico
Correspondence
Editoriais
Editorial
Editorials
Erratum
Letter to the Editor
Letters to the Editor
Original Article
Original Article - Basic Research
Original Article - Neonatologia
Original Articles
Original Articles - Basic Research
Original Articles - Clinical Research
Relato de Caso
Relatos de Caso
Research Letter
Review
Review Article
Special Article
Special Articles
Viewpoint
Year / Volume
2024; v.36
2023; v.35
2022; v.34
2021; v.33
2020; v.32
2019; v.31
2018; v.30
2017; v.29
2016; v.28
2015; v.27
2014; v.26
2013; v.25
2012; v.24
2011; v.23
2010; v.22
2009; v.21
2008; v.20
2007; v.19
2006; v.18
ISSUE